Nature Methods

Nature Methods offers a unique interdisciplinary forum for the publication of novel methods. Nature Methods focuses on the life sciences, combining practical, technique-driven subject matter with rigorous peer-review standards to ensure that readers are consistently presented with only the most valuable and highest quality methodological research. The journal offers its readers primary research papers as well as an array of opinions, reviews and short journalistic pieces to provide busy researchers with a broad, yet easily absorbed perspective of important methodological developments in the life sciences.

ResolVI: addressing noise and bias in spatial transcriptomics

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Solid-state nanopore sensing: the next workhorse of biophysical characterization

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NanoTS: a deep learning tool for accurate SNP calling in nanopore long-read transcriptome data

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SVPG: a pangenome-based structural variant detection approach and rapid augmentation of pangenome graphs with new samples

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Engaging figures

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When a laser beam hits an electron beam

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CFM: confinement force microscopy—a dynamic, precise and stable microconfiner for traction force microscopy in spatial confinement

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SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations

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